HMG 75IU

HMG 75IU

HMG-75IU (Human Menopausal Gonadotropin) is a biologically active preparation containing both follicle-stimulating hormone (FSH) and luteinising hormone (LH). Sourced and standardised for consistent activity, HMG provides a combined gonadotropin profile that is commonly used as a laboratory reagent for exploring pituitary–gonadal axis function, gametogenesis, and steroidogenic signalling. Supplied as a lyophilised preparation, this product is formulated for laboratory research only.

Research Focus and Areas of Interest

1. Endocrine Regulation

HMG offers a controlled means to model pituitary control over gonadal activity. It is used to probe feedback loops between the hypothalamus, pituitary and gonads, and to study downstream steroidogenesis in ovarian and testicular tissues.

2. Follicular Development & Oocyte Studies

Because it supplies both FSH and LH activity, HMG is widely used in research on follicle recruitment, maturation and oocyte physiology. It allows evaluation of hormone-driven follicular dynamics in vitro and in controlled animal models.

3. Spermatogenesis & Testicular Function

In male reproductive research, HMG is employed to assess spermatogenic responses, Sertoli cell signalling and the role of gonadotropins in testicular steroid production and germ cell development.

4. Receptor Signalling Pathways

HMG is useful for studying gonadotropin receptor activation, G-protein coupled signalling cascades and transcriptional responses in gonadal tissues — valuable when mapping mechanisms underlying infertility or hormone-dependent cell function.

5. Assisted Reproduction Model Systems

Researchers use HMG in experimental assisted-reproduction protocols to model stimulation regimens, follicular synchronisation and to explore effects on embryo quality under laboratory conditions.

Conclusion

HMG-75IU is a versatile, research-grade gonadotropin preparation enabling detailed study of reproductive endocrinology, gametogenesis and hormone-dependent signalling. It is supplied solely for laboratory research and is not intended for human, therapeutic or veterinary application.

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Technical Information:

• Synonyms: HMG; Human Menopausal Gonadotropin; Gonadotropins; LH/FSH

• Modified Single-Letter Sequence: Not applicable (glycoprotein complex)

• IUPAC Condensed Sequence: Not applicable for heterodimeric glycoproteins

• Molecular Weight: Variable (glycoprotein complex; depends on glycosylation)

• CAS Number: 21888462

• PubChem CID: 61489-71-2

• Further Reference: PubChem Link

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Stability, Source, and Handling

• Stability: Store lyophilised product at -20 °C. Protect from moisture and light.

• Source: Biosynthetic / biologically sourced gonadotropin preparation; supplied with Certificate of Analysis (COA) on request.

• Reconstitution: Reconstitute using bacteriostatic water under aseptic conditions. After reconstitution, aliquot to avoid repeated freeze–thaw cycles. Reconstituted product may be stored short-term at 4 °C as per laboratory protocol.

• Usage: Product is prepared for LABORATORY RESEARCH ONLY. HMG for sale at Pure Peptides UK is limited to scientific research and education — only purchase if you are a licensed researcher.

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